Feline infectious peritonitis (FIP) vaccine has limited efficacy and has been shown in an experimental study conducted by Dr. Fred Scott of Cornell University to enhance susceptibility to, and virulence of, FIP following virulent virus challenge. We now know that FIP is primarily a disease that occurs because of generation of pathogenic coronavirus mutations during replication of an endemic coronavirus carried by the cat. It is usually not a disease that is spread horizontally, as such, from cat to cat. Therefore, any cat carrying any coronavirus has the potential to develop FIP. Fortunately, such mutational events are rare. Because of limited efficacy and concerns about safety, I do not personally use nor recommend this vaccine.
摘自WSAVA ( 世界小動物獸醫學會 ) 2001年年會 Vaccines of the Present and Future 作者 Alice Wolf ( United States )
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